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Magnevist
Magnevist
Magnevist® is an extracellular, 0.5 molar contrast agent for MRI. In 1988, Magnevist® was the first contrast medium almost simultaneously approved for clinical use by the health authorities in Europe, Japan and the USA. The active ingredient in Magnevist® is gadopentetate dimeglumine. Magnevist® contains gadolinium (Gd3+) which is firmly bound in the complex by the DTPA molecule. Gadolinium is a rare earth element, which causes the contrast enhancement in MRI scans. Magnevist® injection causes in T1 sequences a signal intensity increase in the lesion and in T2*-weighted sequences a short lasting signal intensity decrease in first-pass MRI studies.
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